Structural and Functional Cellular Changes Induced by Burkholderia pseudomallei Rhamnolipid
نویسندگان
چکیده
منابع مشابه
Functional characterization of Burkholderia pseudomallei trimeric autotransporters.
Burkholderia pseudomallei is a tier 1 select agent and the causative agent of melioidosis, a severe and often fatal disease with symptoms ranging from acute pneumonia and septic shock to a chronic infection characterized by abscess formation in the lungs, liver, and spleen. Autotransporters (ATs) are exoproteins belonging to the type V secretion system family, with many playing roles in pathoge...
متن کاملSpecificity and functional activity of anti-Burkholderia pseudomallei polysaccharide antibodies.
The lipopolysaccharide (LPS) of Burkholderia pseudomallei, the causative agent of melioidosis, consists of two O-antigenic polysaccharides designated O-PS I and O-PS II. In this study, the O-PS specificity and functional activity of a protective polyclonal antiserum and an immunoglobulin M (IgM) monoclonal antibody were determined. The polyclonal antiserum recognized both O-PS I and O-PS II, wh...
متن کاملStructural and biological diversity of lipopolysaccharides from Burkholderia pseudomallei and Burkholderia thailandensis.
Burkholderia pseudomallei, the etiological agent of melioidosis, is a facultative intracellular pathogen. As B. pseudomallei is a gram-negative bacterium, its outer membrane contains lipopolysaccharide (LPS) molecules, which have been shown to have low-level immunological activities in vitro. In this study, the biological activities of B. pseudomallei LPS were compared to those of Burkholderia ...
متن کاملBurkholderia pseudomallei Misidentified by Automated System
After returning from Thailand, a 35-year-old man from Switzerland was hospitalized with an abscess of the head. Material cultured from the abscess and adjacent bone grew a gram-negative rod, which was misidentified by an automated microbiology system as Burkholderia cepacia. The organism was eventually identified by molecular methods as B. pseudomallei.
متن کاملFatal Burkholderia pseudomallei septicaemia.
Melioidosis, the infection caused by the saprophytic bacterium Burkholderia pseudomallei, is endemic in south-east Asia and northern Australia [1]. Sporadic cases have been reported from the Indian subcontinent and it is an emerging infection in India [2]. A low prevalence of antibodies against melioidosis among hospitalassociated groups in Colombo had been reported in 1976 [3], as well as a re...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2003
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.71.5.2970-2975.2003